Deep learning applies hierarchical layers of hidden variables to construct nonlinear high dimensional predictors. Our goal is to develop and train deep learning architectures for spatio-temporal modeling. Training a deep architecture is achieved by stochastic gradient descent (SGD) and drop-out (DO) for parameter regularization with a goal of minimizing out-of-sample predictive mean squared error. To illustrate our methodology, we predict the sharp discontinuities in traffic flow data, and secondly, we develop a classification rule to predict short-term futures market prices as a function of the order book depth. Finally, we conclude with directions for future research.