n this paper, we describe an integrated framework for autonomous decision making in a dynamic and interactive environment. We model the interactions between the ego agent and its operating environment as a two-player dynamic game, and integrate cognitive behavioral models, Bayesian inference, and receding-horizon optimal control to define a dynamically-evolving decision strategy for the ego agent. Simulation examples representing autonomous vehicle control in three traffic scenarios where the autonomous ego vehicle interacts with a human-driven vehicle are reported.