In multiple-input multiple-output (MIMO) orthogonal frequency division multiplexing (OFDM) systems, representing the whole channel only based on partial subchannels will significantly reduce the channel acquisition overhead. For such a channel mapping task, inspired by the intrinsic coupling across the space and frequency domains, this letter proposes to use interleaved learning with partial antenna and subcarrier characteristics to represent the whole MIMO-OFDM channel. Specifically, we design a complex-domain multilayer perceptron (MLP)-Mixer (CMixer), which utilizes two kinds of complex-domain MLP modules to learn the space and frequency characteristics respectively and then interleaves them to couple the learned properties. The complex-domain computation facilitates the learning on the complex-valued channel data, while the interleaving tightens the coupling of space and frequency domains. These two designs jointly reduce the learning burden, making the physics-inspired CMixer more effective on channel representation learning than existing data-driven approaches. Simulation shows that the proposed scheme brings 4.6~10dB gains in mapping accuracy compared to existing schemes under different settings. Besides, ablation studies show the necessity of complex-domain computation as well as the extent to which the interleaved learning matches the channel properties.