Recent studies have shown the latency and energy consumption of deep neural networks can be significantly improved by splitting the network between the mobile device and cloud. This paper introduces a new deep learning architecture, called BottleNet, for reducing the feature size needed to be sent to the cloud. Furthermore, we propose a training method for compensating for the potential accuracy loss due to the lossy compression of features before transmitting them to the cloud. BottleNet achieves on average 30x improvement in end-to-end latency and 40x improvement in mobile energy consumption compared to the cloud-only approach with negligible accuracy loss.