Attention-Guided Discriminative Region Localization for Bone Age Assessment

Bone age assessment (BAA) is clinically important as it can be used to diagnose endocrine and metabolic disorders during child development. Existing deep learning based methods for classifying bone age generally use the global image as input, or exploit local information by annotating extra bounding boxes or key points. Training with the global image underutilizes discriminative local information, while providing extra annotations is expensive and subjective. In this paper, we propose an attention-guided approach to automatically localize the discriminative regions for BAA without any extra annotations. Specifically, we first train a classification model to learn the attention heat maps of the discriminative regions, finding the hand region, the most discriminative region (the carpal bones), and the next most discriminative region (the metacarpal bones). We then crop these informative local regions from the original image and aggregate different regions for bone age regression. Extensive comparison experiments are conducted on the RSNA pediatric bone age data set. Using no training annotations, our method achieves competitive results compared with existing state-of-the-art semi-automatic deep learning-based methods that require manual annotation. codes are available at \url{https://github.com/chenchao666/Bone-Age-Assessment}.