Abstract:In this work, we proposed AirwayAtlas, which is an end-to-end pipeline for automatic extraction of airway anatomies with lobar, segmental and subsegmental labeling. A compact representation, AirwaySign, is generated based on diverse features of airway branches. Experiments on multi-center datasets validated the effectiveness of AirwayAtlas. We also demonstrated that AirwaySign is a powerful tool for correlation analysis on pulmonary diseases.