Conformal Depression Prediction

While existing depression recognition methods based on deep learning show promise, their practical application is hindered by the lack of trustworthiness, as these deep models are often deployed as \textit{black box} models, leaving us uncertain about the confidence of the model predictions. For high-risk clinical applications like depression recognition, uncertainty quantification is essential in decision-making. In this paper, we introduce conformal depression prediction (CDP), a depression recognition method with uncertainty quantification based on conformal prediction (CP), giving valid confidence intervals with theoretical coverage guarantees for the model predictions. CDP is a plug-and-play module that requires neither model retraining nor an assumption about the depression data distribution. As CDP provides only an average performance guarantee across all inputs rather than per-input performance guarantee, we propose CDP-ACC, an improved conformal prediction with approximate conditional coverage. CDP-ACC firstly estimates the prediction distribution through neighborhood relaxation, and then introduces a conformal score function by constructing nested sequences, so as to provide tighter prediction interval for each specific input. We empirically demonstrate the application of uncertainty quantification in depression recognition, and the effectiveness and superiority of CDP and CDP-ACC on the AVEC 2013 and AVEC 2014 datasets

MediCLIP: Adapting CLIP for Few-shot Medical Image Anomaly Detection

In the field of medical decision-making, precise anomaly detection in medical imaging plays a pivotal role in aiding clinicians. However, previous work is reliant on large-scale datasets for training anomaly detection models, which increases the development cost. This paper first focuses on the task of medical image anomaly detection in the few-shot setting, which is critically significant for the medical field where data collection and annotation are both very expensive. We propose an innovative approach, MediCLIP, which adapts the CLIP model to few-shot medical image anomaly detection through self-supervised fine-tuning. Although CLIP, as a vision-language model, demonstrates outstanding zero-/fewshot performance on various downstream tasks, it still falls short in the anomaly detection of medical images. To address this, we design a series of medical image anomaly synthesis tasks to simulate common disease patterns in medical imaging, transferring the powerful generalization capabilities of CLIP to the task of medical image anomaly detection. When only few-shot normal medical images are provided, MediCLIP achieves state-of-the-art performance in anomaly detection and location compared to other methods. Extensive experiments on three distinct medical anomaly detection tasks have demonstrated the superiority of our approach. The code is available at https://github.com/cnulab/MediCLIP.

RealNet: A Feature Selection Network with Realistic Synthetic Anomaly for Anomaly Detection

Self-supervised feature reconstruction methods have shown promising advances in industrial image anomaly detection and localization. Despite this progress, these methods still face challenges in synthesizing realistic and diverse anomaly samples, as well as addressing the feature redundancy and pre-training bias of pre-trained feature. In this work, we introduce RealNet, a feature reconstruction network with realistic synthetic anomaly and adaptive feature selection. It is incorporated with three key innovations: First, we propose Strength-controllable Diffusion Anomaly Synthesis (SDAS), a diffusion process-based synthesis strategy capable of generating samples with varying anomaly strengths that mimic the distribution of real anomalous samples. Second, we develop Anomaly-aware Features Selection (AFS), a method for selecting representative and discriminative pre-trained feature subsets to improve anomaly detection performance while controlling computational costs. Third, we introduce Reconstruction Residuals Selection (RRS), a strategy that adaptively selects discriminative residuals for comprehensive identification of anomalous regions across multiple levels of granularity. We assess RealNet on four benchmark datasets, and our results demonstrate significant improvements in both Image AUROC and Pixel AUROC compared to the current state-o-the-art methods. The code, data, and models are available at https://github.com/cnulab/RealNet.

Masked Contrastive Reconstruction for Cross-modal Medical Image-Report Retrieval

Cross-modal medical image-report retrieval task plays a significant role in clinical diagnosis and various medical generative tasks. Eliminating heterogeneity between different modalities to enhance semantic consistency is the key challenge of this task. The current Vision-Language Pretraining (VLP) models, with cross-modal contrastive learning and masked reconstruction as joint training tasks, can effectively enhance the performance of cross-modal retrieval. This framework typically employs dual-stream inputs, using unmasked data for cross-modal contrastive learning and masked data for reconstruction. However, due to task competition and information interference caused by significant differences between the inputs of the two proxy tasks, the effectiveness of representation learning for intra-modal and cross-modal features is limited. In this paper, we propose an efficient VLP framework named Masked Contrastive and Reconstruction (MCR), which takes masked data as the sole input for both tasks. This enhances task connections, reducing information interference and competition between them, while also substantially decreasing the required GPU memory and training time. Moreover, we introduce a new modality alignment strategy named Mapping before Aggregation (MbA). Unlike previous methods, MbA maps different modalities to a common feature space before conducting local feature aggregation, thereby reducing the loss of fine-grained semantic information necessary for improved modality alignment. Qualitative and quantitative experiments conducted on the MIMIC-CXR dataset validate the effectiveness of our approach, demonstrating state-of-the-art performance in medical cross-modal retrieval tasks.

Weakly Supervised Anomaly Detection for Chest X-Ray Image

Chest X-Ray (CXR) examination is a common method for assessing thoracic diseases in clinical applications. While recent advances in deep learning have enhanced the significance of visual analysis for CXR anomaly detection, current methods often miss key cues in anomaly images crucial for identifying disease regions, as they predominantly rely on unsupervised training with normal images. This letter focuses on a more practical setup in which few-shot anomaly images with only image-level labels are available during training. For this purpose, we propose WSCXR, a weakly supervised anomaly detection framework for CXR. WSCXR firstly constructs sets of normal and anomaly image features respectively. It then refines the anomaly image features by eliminating normal region features through anomaly feature mining, thus fully leveraging the scarce yet crucial features of diseased areas. Additionally, WSCXR employs a linear mixing strategy to augment the anomaly features, facilitating the training of anomaly detector with few-shot anomaly images. Experiments on two CXR datasets demonstrate the effectiveness of our approach.

Confidence-Calibrated Face and Kinship Verification

In this paper, we investigate the problem of predictive confidence in face and kinship verification. Most existing face and kinship verification methods focus on accuracy performance while ignoring confidence estimation for their prediction results. However, confidence estimation is essential for modeling reliability in such high-risk tasks. To address this issue, we first introduce a novel yet simple confidence measure for face and kinship verification, which allows the verification models to transform the similarity score into a confidence score for a given face pair. We further propose a confidence-calibrated approach called angular scaling calibration (ASC). ASC is easy to implement and can be directly applied to existing face and kinship verification models without model modifications, yielding accuracy-preserving and confidence-calibrated probabilistic verification models. To the best of our knowledge, our approach is the first general confidence-calibrated solution to face and kinship verification in a modern context. We conduct extensive experiments on four widely used face and kinship verification datasets, and the results demonstrate the effectiveness of our approach.