Material decomposition for dual-energy propagation-based phase-contrast CT

Material decomposition refers to using the energy dependence of material physical properties to differentiate materials in a sample, which is a very important application in computed tomography(CT). In propagation-based X-ray phase-contrast CT, the phase retrieval and Reconstruction are always independent. Moreover, like in conventional CT, the material decomposition methods in this technique can be classified into two types based on pre-reconstruction and post-reconstruction (two-step). The CT images often suffer from noise and artifacts in those methods because of no feedback and correction from the intensity data. This work investigates an iterative method to obtain material decomposition directly from the intensity data in different energies, which means that we perform phase retrieval, reconstruction and material decomposition in a one step. Fresnel diffraction is applied to forward propagation and CT images interact with this intensity data throughout the iterative process. Experiments results demonstrate that compared with two-step methods, the proposed method is superior in accurate material decomposition and noise reduction.

One-step Method for Material Quantitation using In-line Tomography with Single Scanning

Objective: Quantitative technique based on In-line phase-contrast computed tomography with single scanning attracts more attention in application due to the flexibility of the implementation. However, the quantitative results usually suffer from artifacts and noise, since the phase retrieval and reconstruction are independent ("two-steps") without feedback from the original data. Our goal is to develop a method for material quantitative imaging based on a priori information specifically for the single-scanning data. Method: An iterative method that directly reconstructs the refractive index decrement delta and imaginary beta of the object from observed data ("one-step") within single object-to-detector distance (ODD) scanning. Simultaneously, high-quality quantitative reconstruction results are obtained by using a linear approximation that achieves material decomposition in the iterative process. Results: By comparing the equivalent atomic number of the material decomposition results in experiments, the accuracy of the proposed method is greater than 97.2%. Conclusion: The quantitative reconstruction and decomposition results are effectively improved, and there are feedback and corrections during the iteration, which effectively reduce the impact of noise and errors. Significance: This algorithm has the potential for quantitative imaging research, especially for imaging live samples and human breast preclinical studies.