Graph Classification and Radiomics Signature for Identification of Tuberculous Meningitis

Introduction: Tuberculous meningitis (TBM) is a serious brain infection caused by Mycobacterium tuberculosis, characterized by inflammation of the meninges covering the brain and spinal cord. Diagnosis often requires invasive lumbar puncture (LP) and cerebrospinal fluid (CSF) analysis. Objectives: This study aims to classify TBM patients using T1-weighted (T1w) non-contrast Magnetic Resonance Imaging (MRI) scans. We hypothesize that specific brain regions, such as the interpeduncular cisterns, bone, and corpus callosum, contain visual markers that can non-invasively distinguish TBM patients from healthy controls. We propose a novel Pixel-array Graphs Classifier (PAG-Classifier) that leverages spatial relationships between neighbouring 3D pixels in a graph-based framework to extract significant features through eigen decomposition. These features are then used to train machine learning classifiers for effective patient classification. We validate our approach using a radiomics-based methodology, classifying TBM patients based on relevant radiomics features. Results: We utilized an internal dataset consisting of 52 scans, 32 from confirmed TBM patients based on mycobacteria detection in CSF, and 20 from healthy individuals. We achieved a 5-fold cross-validated average F1 score of 85.71% for cistern regions with our PAG-Classifier and 92.85% with the radiomics features classifier, surpassing current state-of-the-art benchmarks by 15% and 22%, respectively. However, bone and corpus callosum regions showed poor classification effectiveness, with average F1 scores below 50%. Conclusion: Our study suggests that algorithms like the PAG-Classifier serve as effective tools for non-invasive TBM analysis, particularly by targeting the interpeduncular cistern. Findings indicate that the bone and corpus callosum regions lack distinctive patterns for differentiation.

Using Computer Vision to enhance Safety of Workforce in Manufacturing in a Post COVID World

The COVID-19 pandemic forced governments across the world to impose lockdowns to prevent virus transmissions. This resulted in the shutdown of all economic activity and accordingly the production at manufacturing plants across most sectors was halted. While there is an urgency to resume production, there is an even greater need to ensure the safety of the workforce at the plant site. Reports indicate that maintaining social distancing and wearing face masks while at work clearly reduces the risk of transmission. We decided to use computer vision on CCTV feeds to monitor worker activity and detect violations which trigger real time voice alerts on the shop floor. This paper describes an efficient and economic approach of using AI to create a safe environment in a manufacturing setup. We demonstrate our approach to build a robust social distancing measurement algorithm using a mix of modern-day deep learning and classic projective geometry techniques. We have deployed our solution at manufacturing plants across the Aditya Birla Group (ABG). We have also described our face mask detection approach which provides a high accuracy across a range of customized masks.