Abstract:Speech-based depression detection tools could help early screening of depression. Here, we address two issues that may hinder the clinical practicality of such tools: segment-level labelling noise and a lack of model interpretability. We propose a speech-level Audio Spectrogram Transformer to avoid segment-level labelling. We observe that the proposed model significantly outperforms a segment-level model, providing evidence for the presence of segment-level labelling noise in audio modality and the advantage of longer-duration speech analysis for depression detection. We introduce a frame-based attention interpretation method to extract acoustic features from prediction-relevant waveform signals for interpretation by clinicians. Through interpretation, we observe that the proposed model identifies reduced loudness and F0 as relevant signals of depression, which aligns with the speech characteristics of depressed patients documented in clinical studies.
Abstract:Depression is a common mental disorder. Automatic depression detection tools using speech, enabled by machine learning, help early screening of depression. This paper addresses two limitations that may hinder the clinical implementations of such tools: noise resulting from segment-level labelling and a lack of model interpretability. We propose a bi-modal speech-level transformer to avoid segment-level labelling and introduce a hierarchical interpretation approach to provide both speech-level and sentence-level interpretations, based on gradient-weighted attention maps derived from all attention layers to track interactions between input features. We show that the proposed model outperforms a model that learns at a segment level ($p$=0.854, $r$=0.947, $F1$=0.947 compared to $p$=0.732, $r$=0.808, $F1$=0.768). For model interpretation, using one true positive sample, we show which sentences within a given speech are most relevant to depression detection; and which text tokens and Mel-spectrogram regions within these sentences are most relevant to depression detection. These interpretations allow clinicians to verify the validity of predictions made by depression detection tools, promoting their clinical implementations.