Federated Learning in Chemical Engineering: A Tutorial on a Framework for Privacy-Preserving Collaboration Across Distributed Data Sources

Federated Learning (FL) is a decentralized machine learning approach that has gained attention for its potential to enable collaborative model training across clients while protecting data privacy, making it an attractive solution for the chemical industry. This work aims to provide the chemical engineering community with an accessible introduction to the discipline. Supported by a hands-on tutorial and a comprehensive collection of examples, it explores the application of FL in tasks such as manufacturing optimization, multimodal data integration, and drug discovery while addressing the unique challenges of protecting proprietary information and managing distributed datasets. The tutorial was built using key frameworks such as $\texttt{Flower}$ and $\texttt{TensorFlow Federated}$ and was designed to provide chemical engineers with the right tools to adopt FL in their specific needs. We compare the performance of FL against centralized learning across three different datasets relevant to chemical engineering applications, demonstrating that FL will often maintain or improve classification performance, particularly for complex and heterogeneous data. We conclude with an outlook on the open challenges in federated learning to be tackled and current approaches designed to remediate and improve this framework.

Federated Learning with Quantum Computing and Fully Homomorphic Encryption: A Novel Computing Paradigm Shift in Privacy-Preserving ML

The widespread deployment of products powered by machine learning models is raising concerns around data privacy and information security worldwide. To address this issue, Federated Learning was first proposed as a privacy-preserving alternative to conventional methods that allow multiple learning clients to share model knowledge without disclosing private data. A complementary approach known as Fully Homomorphic Encryption (FHE) is a quantum-safe cryptographic system that enables operations to be performed on encrypted weights. However, implementing mechanisms such as these in practice often comes with significant computational overhead and can expose potential security threats. Novel computing paradigms, such as analog, quantum, and specialized digital hardware, present opportunities for implementing privacy-preserving machine learning systems while enhancing security and mitigating performance loss. This work instantiates these ideas by applying the FHE scheme to a Federated Learning Neural Network architecture that integrates both classical and quantum layers.