MTDT: A Multi-Task Deep Learning Digital Twin

Traffic congestion has significant impacts on both the economy and the environment. Measures of Effectiveness (MOEs) have long been the standard for evaluating the level of service and operational efficiency of traffic intersections. However, the scarcity of traditional high-resolution loop detector data (ATSPM) presents challenges in accurately measuring MOEs or capturing the intricate temporospatial characteristics inherent in urban intersection traffic. In response to this challenge, we have introduced the Multi-Task Deep Learning Digital Twin (MTDT) as a solution for multifaceted and precise intersection traffic flow simulation. MTDT enables accurate, fine-grained estimation of loop detector waveform time series for each lane of movement, alongside successful estimation of several MOEs for each lane group associated with a traffic phase concurrently and for all approaches of an arbitrary urban intersection. Unlike existing deep learning methodologies, MTDT distinguishes itself through its adaptability to local temporal and spatial features, such as signal timing plans, intersection topology, driving behaviors, and turning movement counts. While maintaining a straightforward design, our model emphasizes the advantages of multi-task learning in traffic modeling. By consolidating the learning process across multiple tasks, MTDT demonstrates reduced overfitting, increased efficiency, and enhanced effectiveness by sharing representations learned by different tasks. Furthermore, our approach facilitates sequential computation and lends itself to complete parallelization through GPU implementation. This not only streamlines the computational process but also enhances scalability and performance.

Graph Attention Network for Lane-Wise and Topology-Invariant Intersection Traffic Simulation

Traffic congestion has significant economic, environmental, and social ramifications. Intersection traffic flow dynamics are influenced by numerous factors. While microscopic traffic simulators are valuable tools, they are computationally intensive and challenging to calibrate. Moreover, existing machine-learning approaches struggle to provide lane-specific waveforms or adapt to intersection topology and traffic patterns. In this study, we propose two efficient and accurate "Digital Twin" models for intersections, leveraging Graph Attention Neural Networks (GAT). These attentional graph auto-encoder digital twins capture temporal, spatial, and contextual aspects of traffic within intersections, incorporating various influential factors such as high-resolution loop detector waveforms, signal state records, driving behaviors, and turning-movement counts. Trained on diverse counterfactual scenarios across multiple intersections, our models generalize well, enabling the estimation of detailed traffic waveforms for any intersection approach and exit lanes. Multi-scale error metrics demonstrate that our models perform comparably to microsimulations. The primary application of our study lies in traffic signal optimization, a pivotal area in transportation systems research. These lightweight digital twins can seamlessly integrate into corridor and network signal timing optimization frameworks. Furthermore, our study's applications extend to lane reconfiguration, driving behavior analysis, and facilitating informed decisions regarding intersection safety and efficiency enhancements. A promising avenue for future research involves extending this approach to urban freeway corridors and integrating it with measures of effectiveness metrics.

LAVA: Granular Neuron-Level Explainable AI for Alzheimer's Disease Assessment from Fundus Images

Alzheimer's Disease (AD) is a progressive neurodegenerative disease and the leading cause of dementia. Early diagnosis is critical for patients to benefit from potential intervention and treatment. The retina has been hypothesized as a diagnostic site for AD detection owing to its anatomical connection with the brain. Developed AI models for this purpose have yet to provide a rational explanation about the decision and neither infer the stage of disease's progression. Along this direction, we propose a novel model-agnostic explainable-AI framework, called Granular Neuron-level Explainer (LAVA), an interpretation prototype that probes into intermediate layers of the Convolutional Neural Network (CNN) models to assess the AD continuum directly from the retinal imaging without longitudinal or clinical evaluation. This method is applied to validate the retinal vasculature as a biomarker and diagnostic modality for Alzheimer's Disease (AD) evaluation. UK Biobank cognitive tests and vascular morphological features suggest LAVA shows strong promise and effectiveness in identifying AD stages across the progression continuum.