Abstract:Multimodal single-cell technologies enable the simultaneous collection of diverse data types from individual cells, enhancing our understanding of cellular states. However, the integration of these datatypes and modeling the interrelationships between modalities presents substantial computational and analytical challenges in disease biomarker detection and drug discovery. Established practices rely on isolated methodologies to investigate individual molecular aspects separately, often resulting in inaccurate analyses. To address these obstacles, distinct Machine Learning Techniques are leveraged, each of its own kind to model the co-variation of DNA to RNA, and finally to surface proteins in single cells during hematopoietic stem cell development, which simplifies understanding of underlying cellular mechanisms and immune responses. Experiments conducted on a curated subset of a 300,000-cell time course dataset, highlights the exceptional performance of Echo State Networks, boasting a remarkable state-of-the-art correlation score of 0.94 and 0.895 on Multi-omic and CiteSeq datasets. Beyond the confines of this study, these findings hold promise for advancing comprehension of cellular differentiation and function, leveraging the potential of Machine Learning.
Abstract:The importance of predicting stock market prices cannot be overstated. It is a pivotal task for investors and financial institutions as it enables them to make informed investment decisions, manage risks, and ensure the stability of the financial system. Accurate stock market predictions can help investors maximize their returns and minimize their losses, while financial institutions can use this information to develop effective risk management policies. However, stock market prediction is a challenging task due to the complex nature of the stock market and the multitude of factors that can affect stock prices. As a result, advanced technologies such as deep learning are being increasingly utilized to analyze vast amounts of data and provide valuable insights into the behavior of the stock market. While deep learning has shown promise in accurately predicting stock prices, there is still much research to be done in this area.