PhysRFANet: Physics-Guided Neural Network for Real-Time Prediction of Thermal Effect During Radiofrequency Ablation Treatment

Radiofrequency ablation (RFA) is a widely used minimally invasive technique for ablating solid tumors. Achieving precise personalized treatment necessitates feedback information on in situ thermal effects induced by the RFA procedure. While computer simulation facilitates the prediction of electrical and thermal phenomena associated with RFA, its practical implementation in clinical settings is hindered by high computational demands. In this paper, we propose a physics-guided neural network model, named PhysRFANet, to enable real-time prediction of thermal effect during RFA treatment. The networks, designed for predicting temperature distribution and the corresponding ablation lesion, were trained using biophysical computational models that integrated electrostatics, bio-heat transfer, and cell necrosis, alongside magnetic resonance (MR) images of breast cancer patients. Validation of the computational model was performed through experiments on ex vivo bovine liver tissue. Our model demonstrated a 96% Dice score in predicting the lesion volume and an RMSE of 0.4854 for temperature distribution when tested with foreseen tumor images. Notably, even with unforeseen images, it achieved a 93% Dice score for the ablation lesion and an RMSE of 0.6783 for temperature distribution. All networks were capable of inferring results within 10 ms. The presented technique, applied to optimize the placement of the electrode for a specific target region, holds significant promise in enhancing the safety and efficacy of RFA treatments.

PU-EdgeFormer: Edge Transformer for Dense Prediction in Point Cloud Upsampling

Despite the recent development of deep learning-based point cloud upsampling, most MLP-based point cloud upsampling methods have limitations in that it is difficult to train the local and global structure of the point cloud at the same time. To solve this problem, we present a combined graph convolution and transformer for point cloud upsampling, denoted by PU-EdgeFormer. The proposed method constructs EdgeFormer unit that consists of graph convolution and multi-head self-attention modules. We employ graph convolution using EdgeConv, which learns the local geometry and global structure of point cloud better than existing point-to-feature method. Through in-depth experiments, we confirmed that the proposed method has better point cloud upsampling performance than the existing state-of-the-art method in both subjective and objective aspects. The code is available at https://github.com/dohoon2045/PU-EdgeFormer.