Abstract:Recently, the scientific progress of Advanced Driver Assistance System solutions (ADAS) has played a key role in enhancing the overall safety of driving. ADAS technology enables active control of vehicles to prevent potentially risky situations. An important aspect that researchers have focused on is the analysis of the driver attention level, as recent reports confirmed a rising number of accidents caused by drowsiness or lack of attentiveness. To address this issue, various studies have suggested monitoring the driver physiological state, as there exists a well-established connection between the Autonomic Nervous System (ANS) and the level of attention. For our study, we designed an innovative bio-sensor comprising near-infrared LED emitters and photo-detectors, specifically a Silicon PhotoMultiplier device. This allowed us to assess the driver physiological status by analyzing the associated PhotoPlethysmography (PPG) signal.Furthermore, we developed an embedded time-domain hyper-filtering technique in conjunction with a 1D Temporal Convolutional architecture that embdes a progressive dilation setup. This integrated system enables near real-time classification of driver drowsiness, yielding remarkable accuracy levels of approximately 96%.
Abstract:Immunotherapy emerges as promising approach for treating cancer. Encouraging findings have validated the efficacy of immunotherapy medications in addressing tumors, resulting in prolonged survival rates and notable reductions in toxicity compared to conventional chemotherapy methods. However, the pool of eligible patients for immunotherapy remains relatively small, indicating a lack of comprehensive understanding regarding the physiological mechanisms responsible for favorable treatment response in certain individuals while others experience limited benefits. To tackle this issue, the authors present an innovative strategy that harnesses a non-linear cellular architecture in conjunction with a deep downstream classifier. This approach aims to carefully select and enhance 2D features extracted from chest-abdomen CT images, thereby improving the prediction of treatment outcomes. The proposed pipeline has been meticulously designed to seamlessly integrate with an advanced embedded Point of Care system. In this context, the authors present a compelling case study focused on Metastatic Urothelial Carcinoma (mUC), a particularly aggressive form of cancer. Performance evaluation of the proposed approach underscores its effectiveness, with an impressive overall accuracy of approximately 93%