Abstract:Research on decision support applications in healthcare, such as those related to diagnosis, prediction, treatment planning, etc., have seen enormously increased interest recently. This development is thanks to the increase in data availability as well as advances in artificial intelligence and machine learning research. Highly promising research examples are published daily. However, at the same time, there are some unrealistic expectations with regards to the requirements for reliable development and objective validation that is needed in healthcare settings. These expectations may lead to unmet schedules and disappointments (or non-uptake) at the end-user side. It is the aim of this tutorial to provide practical guidance on how to assess performance reliably and efficiently and avoid common traps. Instead of giving a list of do's and don't s, this tutorial tries to build a better understanding behind these do's and don't s and presents both the most relevant performance evaluation criteria as well as how to compute them. Along the way, we will indicate common mistakes and provide references discussing various topics more in-depth.
Abstract:Recent advancements in machine learning research, i.e., deep learning, introduced methods that excel conventional algorithms as well as humans in several complex tasks, ranging from detection of objects in images and speech recognition to playing difficult strategic games. However, the current methodology of machine learning research and consequently, implementations of the real-world applications of such algorithms, seems to have a recurring HARKing (Hypothesizing After the Results are Known) issue. In this work, we elaborate on the algorithmic, economic and social reasons and consequences of this phenomenon. We present examples from current common practices of conducting machine learning research (e.g. avoidance of reporting negative results) and failure of generalization ability of the proposed algorithms and datasets in actual real-life usage. Furthermore, a potential future trajectory of machine learning research and development from the perspective of accountable, unbiased, ethical and privacy-aware algorithmic decision making is discussed. We would like to emphasize that with this discussion we neither claim to provide an exhaustive argumentation nor blame any specific institution or individual on the raised issues. This is simply a discussion put forth by us, insiders of the machine learning field, reflecting on us.