Abstract:The trustworthiness of Robots and Autonomous Systems (RAS) has gained a prominent position on many research agendas towards fully autonomous systems. This research systematically explores, for the first time, the key facets of human-centered AI (HAI) for trustworthy RAS. In this article, five key properties of a trustworthy RAS initially have been identified. RAS must be (i) safe in any uncertain and dynamic surrounding environments; (ii) secure, thus protecting itself from any cyber-threats; (iii) healthy with fault tolerance; (iv) trusted and easy to use to allow effective human-machine interaction (HMI), and (v) compliant with the law and ethical expectations. Then, the challenges in implementing trustworthy autonomous system are analytically reviewed, in respects of the five key properties, and the roles of AI technologies have been explored to ensure the trustiness of RAS with respects to safety, security, health and HMI, while reflecting the requirements of ethics in the design of RAS. While applications of RAS have mainly focused on performance and productivity, the risks posed by advanced AI in RAS have not received sufficient scientific attention. Hence, a new acceptance model of RAS is provided, as a framework for requirements to human-centered AI and for implementing trustworthy RAS by design. This approach promotes human-level intelligence to augment human's capacity. while focusing on contributions to humanity.