Abstract:Autism spectrum disorder (ASD) is a developmental condition that presents significant challenges in social interaction, communication, and behavior. Early intervention plays a pivotal role in enhancing cognitive abilities and reducing autistic symptoms in children with ASD. Numerous clinical studies have highlighted distinctive facial characteristics that distinguish ASD children from typically developing (TD) children. In this study, we propose a practical solution for ASD screening using facial images using YoloV8 model. By employing YoloV8, a deep learning technique, on a dataset of Kaggle, we achieved exceptional results. Our model achieved a remarkable 89.64% accuracy in classification and an F1-score of 0.89. Our findings provide support for the clinical observations regarding facial feature discrepancies between children with ASD. The high F1-score obtained demonstrates the potential of deep learning models in screening children with ASD. We conclude that the newest version of YoloV8 which is usually used for object detection can be used for classification problem of Austistic and Non-autistic images.