This paper introduces a novel Nussbaum function-based PID control for robotic manipulators. The integration of the Nussbaum function into the PID framework provides a solution with a simple structure that effectively tackles the challenge of unknown control directions. Stability is achieved through a combination of neural network-based estimation and Lyapunov analysis, facilitating automatic gain adjustment without the need for system dynamics. Our approach offers a gain determination with minimum parameter requirements, significantly reducing the complexity and enhancing the efficiency of robotic manipulator control. The paper guarantees that all signals within the closed-loop system remain bounded. Lastly, numerical simulations validate the theoretical framework, confirming the effectiveness of the proposed control strategy in enhancing robotic manipulator control.