Signal processing tasks as fundamental as sampling, reconstruction, minimum mean-square error interpolation and prediction can be viewed under the prism of reproducing kernel Hilbert spaces. Endowing this vantage point with contemporary advances in sparsity-aware modeling and processing, promotes the nonparametric basis pursuit advocated in this paper as the overarching framework for the confluence of kernel-based learning (KBL) approaches leveraging sparse linear regression, nuclear-norm regularization, and dictionary learning. The novel sparse KBL toolbox goes beyond translating sparse parametric approaches to their nonparametric counterparts, to incorporate new possibilities such as multi-kernel selection and matrix smoothing. The impact of sparse KBL to signal processing applications is illustrated through test cases from cognitive radio sensing, microarray data imputation, and network traffic prediction.