Compute-in-memory (CIM) has been proposed to accelerate the convolution neural network (CNN) computation by implementing parallel multiply and accumulation in analog domain. However, the subsequent processing is still preferred to be performed in digital domain. This makes the analog to digital converter (ADC) critical in CIM architectures. One drawback is the ADC error introduced by process variation. While research efforts are being made to improve ADC design to reduce the offset, we find that the accuracy loss introduced by the ADC error could be recovered by model weight finetune. In addition to compensate ADC offset, on-chip weight finetune could be leveraged to provide additional protection for adversarial attack that aims to fool the inference engine with manipulated input samples. Our evaluation results show that by adapting the model weights to the specific ADC offset pattern to each chip, the transferability of the adversarial attack is suppressed. For a chip being attacked by the C&W method, the classification for CIFAR-10 dataset will drop to almost 0%. However, when applying the similarly generated adversarial examples to other chips, the accuracy could still maintain more than 62% and 85% accuracy for VGG-8 and DenseNet-40, respectively.