Deep convolutional neural networks have achieved great progress in image denoising tasks. However, their complicated architectures and heavy computational cost hinder their deployments on a mobile device. Some recent efforts in designing lightweight denoising networks focus on reducing either FLOPs (floating-point operations) or the number of parameters. However, these metrics are not directly correlated with the on-device latency. By performing extensive analysis and experiments, we identify the network architectures that can fully utilize powerful neural processing units (NPUs) and thus enjoy both low latency and excellent denoising performance. To this end, we propose a mobile-friendly denoising network, namely MFDNet. The experiments show that MFDNet achieves state-of-the-art performance on real-world denoising benchmarks SIDD and DND under real-time latency on mobile devices. The code and pre-trained models will be released.