Face manipulation methods develop rapidly in recent years, which can generate high quality manipulated face images. However, detection methods perform not well on data produced by state-of-the-art manipulation methods, and they lack of generalization ability. In this paper, we propose a novel manipulated face detector, which is based on spatial and frequency domain combination and attention mechanism. Spatial domain features are extracted by facial semantic segmentation, and frequency domain features are extracted by Discrete Fourier Transform. We use features both in spatial domain and frequency domain as inputs in proposed model. And we add attention-based layers to backbone networks, in order to improve its generalization ability. We evaluate proposed model on several datasets and compare it with other state-of-the-art manipulated face detection methods. The results show our model performs best on both seen and unseen data.