The best current methods for exactly computing the number of satisfying assignments, or the satisfying probability, of Boolean formulas can be seen, either directly or indirectly, as building 'decision-DNNF' (decision decomposable negation normal form) representations of the input Boolean formulas. Decision-DNNFs are a special case of 'd-DNNF's where 'd' stands for 'deterministic'. We show that any decision-DNNF can be converted into an equivalent 'FBDD' (free binary decision diagram) -- also known as a 'read-once branching program' (ROBP or 1-BP) -- with only a quasipolynomial increase in representation size in general, and with only a polynomial increase in size in the special case of monotone k-DNF formulas. Leveraging known exponential lower bounds for FBDDs, we then obtain similar exponential lower bounds for decision-DNNFs which provide lower bounds for the recent algorithms. We also separate the power of decision-DNNFs from d-DNNFs and a generalization of decision-DNNFs known as AND-FBDDs. Finally we show how these imply exponential lower bounds for natural problems associated with probabilistic databases.