One of the major bottlenecks in high-resolution Earth Observation (EO) space systems is the downlink between the satellite and the ground. Due to hardware limitations, on-board power limitations or ground-station operation costs, there is a strong need to reduce the amount of data transmitted. Various processing methods can be used to compress the data. One of them is the use of on-board deep learning to extract relevant information in the data. However, most ground-based deep neural network parameters and computations are performed using single-precision floating-point arithmetic, which is not adapted to the context of on-board processing. We propose to rely on quantized neural networks and study how to combine low precision (mini) floating-point arithmetic with a Quantization-Aware Training methodology. We evaluate our approach with a semantic segmentation task for ship detection using satellite images from the Airbus Ship dataset. Our results show that 6-bit floating-point quantization for both weights and activations can compete with single-precision without significant accuracy degradation. Using a Thin U-Net 32 model, only a 0.3% accuracy degradation is observed with 6-bit minifloat quantization (a 6-bit equivalent integer-based approach leads to a 0.5% degradation). An initial hardware study also confirms the potential impact of such low-precision floating-point designs, but further investigation at the scale of a full inference accelerator is needed before concluding whether they are relevant in a practical on-board scenario.