Inter-Cell Interference Coordination (ICIC) is a promising way to improve energy efficiency in wireless networks, especially where small base stations are densely deployed. However, traditional optimization based ICIC schemes suffer from severe performance degradation with complex interference pattern. To address this issue, we propose a Deep Reinforcement Learning with Deterministic Policy and Target (DRL-DPT) framework for ICIC in wireless networks. DRL-DPT overcomes the main obstacles in applying reinforcement learning and deep learning in wireless networks, i.e. continuous state space, continuous action space and convergence. Firstly, a Deep Neural Network (DNN) is involved as the actor to obtain deterministic power control actions in continuous space. Then, to guarantee the convergence, an online training process is presented, which makes use of a dedicated reward function as the target rule and a policy gradient descent algorithm to adjust DNN weights. Experimental results show that the proposed DRL-DPT framework consistently outperforms existing schemes in terms of energy efficiency and throughput under different wireless interference scenarios. More specifically, it improves up to 15% of energy efficiency with faster convergence rate.