In this paper, we study an unmanned aerial vehicle (UAV) enabled data collection system, where an intelligent reflecting surface (IRS) is deployed to assist in the communication from a cluster of Internet-of-Things (IoT) devices to a UAV in the presence of a jammer. We aim to improve the energy efficiency (EE) via the joint design of UAV trajectory, IRS passive beamforming, device power allocation, and communication scheduling. However, the formulated non-linear fractional programming problem is challenging to solve due to its non-convexity and coupled variables. To overcome the difficulty, we propose an alternating optimization based algorithm to solve it sub-optimally by leveraging Dinkelbach's algorithm, successive convex approximation (SCA) technique, and block coordinate descent (BCD) method. Extensive simulation results show that the proposed design can significantly improve the anti-jamming performance. In particular, for the remote jammer case, the proposed design can largely shorten the flight path and thus decrease the energy consumption via the signal enhancement; while for the local jammer case, which is deemed highly challenging in conventional systems without IRS since the retreating away strategy becomes ineffective, our proposed design even achieves a higher performance gain owing to the efficient jamming signal mitigation.