Space exploration and establishing human presence on other planets demand advanced technology and effective collaboration between robots and astronauts. Efficient space resource utilization is also vital for extraterrestrial settlements. The Collaborative In-Situ Resources Utilisation (CISRU) project has developed a software suite comprising five key modules. The first module manages multi-agent autonomy, facilitating communication between agents and mission control. The second focuses on environment perception, employing AI algorithms for tasks like environment segmentation and object pose estimation. The third module ensures safe navigation, covering obstacle avoidance, social navigation with astronauts, and cooperation among robots. The fourth module addresses manipulation functions, including multi-tool capabilities and tool-changer design for diverse tasks in In-Situ Resources Utilization (ISRU) scenarios. Finally, the fifth module controls cooperative behaviour, incorporating astronaut commands, Mixed Reality interfaces, map fusion, task supervision, and error control. The suite was tested using an astronaut-rover interaction dataset in a planetary environment and GMV SPoT analogue environments. Results demonstrate the advantages of E4 autonomy and AI in space systems, benefiting astronaut-robot collaboration. This paper details CISRU's development, field test preparation, and analysis, highlighting its potential to revolutionize planetary exploration through AI-powered technology.