Mobile health (mHealth) information service makes healthcare management easier for users, who want to increase physical activity and improve health. However, the differences in activity preference among the individual, adherence problems, and uncertainty of future health outcomes may reduce the effect of the mHealth information service. The current health service system usually provides recommendations based on fixed exercise plans that do not satisfy the user specific needs. This paper seeks an efficient way to make physical activity recommendation decisions on physical activity promotion in personalised mHealth information service by establishing data-driven model. In this study, we propose a real-time interaction model to select the optimal exercise plan for the individual considering the time-varying characteristics in maximising the long-term health utility of the user. We construct a framework for mHealth information service system comprising a personalised AI module, which is based on the scientific knowledge about physical activity to evaluate the individual exercise performance, which may increase the awareness of the mHealth artificial intelligence system. The proposed deep reinforcement learning (DRL) methodology combining two classes of approaches to improve the learning capability for the mHealth information service system. A deep learning method is introduced to construct the hybrid neural network combing long-short term memory (LSTM) network and deep neural network (DNN) techniques to infer the individual exercise behavior from the time series data. A reinforcement learning method is applied based on the asynchronous advantage actor-critic algorithm to find the optimal policy through exploration and exploitation.