We use deep reinforcement learning (RL) to optimize a weapons to target assignment (WTA) policy for multi-vehicle hypersonic strike against multiple targets. The objective is to maximize the total value of destroyed targets in each episode. Each randomly generated episode varies the number and initial conditions of the hypersonic strike weapons (HSW) and targets, the value distribution of the targets, and the probability of a HSW being intercepted. We compare the performance of this WTA policy to that of a benchmark WTA policy derived using non-linear integer programming (NLIP), and find that the RL WTA policy gives near optimal performance with a 1000X speedup in computation time, allowing real time operation that facilitates autonomous decision making in the mission end game.