The theory of RKHS provides an elegant framework for supervised learning. It is the foundation of all kernel methods in machine learning. Implicit in its formulation is the use of a quadratic regularizer associated with the underlying inner product which imposes smoothness constraints. In this paper, we consider instead the generalized total-variation (gTV) norm as the sparsity-promoting regularizer. This leads us to propose a new Banach-space framework that justifies the use of generalized LASSO, albeit in a slightly modified version. We prove a representer theorem for multiple-kernel regression (MKR) with gTV regularization. The theorem states that the solutions of MKR have kernel expansions with adaptive positions, while the gTV norm enforces an $\ell_1$ penalty on the coefficients. We discuss the sparsity-promoting effect of the gTV norm which prevents redundancy in the multiple-kernel scenario.