In an era of rapid urbanization and e-commerce growth, efficient parcel delivery methods are crucial. This paper presents a detailed study of the aerodynamics and sensing analysis of drones for parcel delivery. Utilizing Computational Fluid Dynamics (CFD), the study offers a comprehensive airflow analysis, revealing the aerodynamic forces affecting drone stability due to payload capacity. A multidisciplinary approach is employed, integrating mechanical design, control theory, and sensing systems to address the complex issue of parcel positioning. The experimental validation section rigorously tests different size payloads and their positions and impact on drones with maximum thrusts of 2000 gf. The findings prove the drone's capacity to lift a large payload that covers up to 50 percent of the propeller, thereby contributing to optimizing drone designs and sustainable parcel delivery systems. It has been observed that the drone can lift a large payload smoothly when placed above the drone, with an error rate as low as 0.1 percent for roll, pitch, and yaw. This work paved the way for more versatile, real-world applications of drone technology, setting a new standard in the field.