The Yongle Palace murals, as valuable cultural heritage, have suffered varying degrees of damage, making their restoration of significant importance. However, the giant size and unique data of Yongle Palace murals present challenges for existing deep-learning based restoration methods: 1) The distinctive style introduces domain bias in traditional transfer learning-based restoration methods, while the scarcity of mural data further limits the applicability of these methods. 2) Additionally, the giant size of these murals results in a wider range of defect types and sizes, necessitating models with greater adaptability. Consequently, there is a lack of focus on deep learning-based restoration methods for the unique giant murals of Yongle Palace. Here, a 3M-Hybrid model is proposed to address these challenges. Firstly, based on the characteristic that the mural data frequency is prominent in the distribution of low and high frequency features, high and low frequency features are separately abstracted for complementary learning. Furthermore, we integrate a pre-trained Vision Transformer model (VIT) into the CNN module, allowing us to leverage the benefits of a large model while mitigating domain bias. Secondly, we mitigate seam and structural distortion issues resulting from the restoration of large defects by employing a multi-scale and multi-perspective strategy, including data segmentation and fusion. Experimental results demonstrate the efficacy of our proposed model. In regular-sized mural restoration, it improves SSIM and PSNR by 14.61% and 4.73%, respectively, compared to the best model among four representative CNN models. Additionally, it achieves favorable results in the final restoration of giant murals.