Abstract:Justifying draconian measures during the Covid-19 pandemic was difficult not only because of the restriction of individual rights, but also because of its economic impact. The objective of this work is to present a machine learning approach to identify regions that should implement similar health policies. For that end, we successfully developed a system that gives a notion of economic impact given the prediction of new incidental cases through unsupervised learning and time series forecasting. This system was built taking into account computational restrictions and low maintenance requirements in order to improve the system's resilience. Finally this system was deployed as part of a web application for simulation and data analysis of COVID-19, in Colombia, available at (https://covid19.dis.eafit.edu.co).