Abstract:Diffusion models have demonstrated significant potential in speech synthesis tasks, including text-to-speech (TTS) and voice cloning. However, their iterative denoising processes are inefficient and hinder the application of end-to-end optimization with perceptual metrics. In this paper, we propose a novel method of distilling TTS diffusion models with direct end-to-end evaluation metric optimization, achieving state-of-the-art performance. By incorporating Connectionist Temporal Classification (CTC) loss and Speaker Verification (SV) loss, our approach optimizes perceptual evaluation metrics, leading to notable improvements in word error rate and speaker similarity. Our experiments show that DMDSpeech consistently surpasses prior state-of-the-art models in both naturalness and speaker similarity while being significantly faster. Moreover, our synthetic speech has a higher level of voice similarity to the prompt than the ground truth in both human evaluation and objective speaker similarity metric. This work highlights the potential of direct metric optimization in speech synthesis, allowing models to better align with human auditory preferences. The audio samples are available at https://dmdspeech.github.io/.