AnyCXR: Human Anatomy Segmentation of Chest X-ray at Any Acquisition Position using Multi-stage Domain Randomized Synthetic Data with Imperfect Annotations and Conditional Joint Annotation Regularization Learning

Robust anatomical segmentation of chest X-rays (CXRs) remains challenging due to the scarcity of comprehensive annotations and the substantial variability of real-world acquisition conditions. We propose AnyCXR, a unified framework that enables generalizable multi-organ segmentation across arbitrary CXR projection angles using only synthetic supervision. The method combines a Multi-stage Domain Randomization (MSDR) engine, which generates over 100,000 anatomically faithful and highly diverse synthetic radiographs from 3D CT volumes, with a Conditional Joint Annotation Regularization (CAR) learning strategy that leverages partial and imperfect labels by enforcing anatomical consistency in a latent space. Trained entirely on synthetic data, AnyCXR achieves strong zero-shot generalization on multiple real-world datasets, providing accurate delineation of 54 anatomical structures in PA, lateral, and oblique views. The resulting segmentation maps support downstream clinical tasks, including automated cardiothoracic ratio estimation, spine curvature assessment, and disease classification, where the incorporation of anatomical priors improves diagnostic performance. These results demonstrate that AnyCXR establishes a scalable and reliable foundation for anatomy-aware CXR analysis and offers a practical pathway toward reducing annotation burdens while improving robustness across diverse imaging conditions.

Quantum Circuit Synthesis and Compilation Optimization: Overview and Prospects

Quantum computing is regarded as a promising paradigm that may overcome the current computational power bottlenecks in the post-Moore era. The increasing maturity of quantum processors, especially superconducting ones, provides more possibilities for the development and implementation of quantum algorithms. As the crucial stages for quantum algorithm implementation, the logic circuit design and quantum compiling have also received significant attention, which covers key technologies such as quantum logic circuit synthesis (also widely known as quantum architecture search) and optimization, as well as qubit mapping and routing. Recent studies suggest that the scale and precision of related algorithms are steadily increasing, especially with the integration of artificial intelligence methods. In this survey, we systematically review and summarize a vast body of literature, exploring the feasibility of an integrated design and optimization scheme that spans from the algorithmic level to quantum hardware, combining the steps of logic circuit design and compilation optimization. Leveraging the exceptional cognitive and learning capabilities of AI algorithms, one can reduce manual design costs, enhance the precision and efficiency of execution, and facilitate the implementation and validation of the superiority of quantum algorithms on hardware.