Abstract:The integration of quantum computing into classical machine learning architectures has emerged as a promising approach to enhance model efficiency and computational capacity. In this work, we introduce the Quantum Kernel-Based Long Short-Term Memory (QK-LSTM) network, which utilizes quantum kernel functions within the classical LSTM framework to capture complex, non-linear patterns in sequential data. By embedding input data into a high-dimensional quantum feature space, the QK-LSTM model reduces the reliance on large parameter sets, achieving effective compression while maintaining accuracy in sequence modeling tasks. This quantum-enhanced architecture demonstrates efficient convergence, robust loss minimization, and model compactness, making it suitable for deployment in edge computing environments and resource-limited quantum devices (especially in the NISQ era). Benchmark comparisons reveal that QK-LSTM achieves performance on par with classical LSTM models, yet with fewer parameters, underscoring its potential to advance quantum machine learning applications in natural language processing and other domains requiring efficient temporal data processing.
Abstract:This paper introduces CompressedMediQ, a novel hybrid quantum-classical machine learning pipeline specifically developed to address the computational challenges associated with high-dimensional multi-class neuroimaging data analysis. Standard neuroimaging datasets, such as 4D MRI data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) and Neuroimaging in Frontotemporal Dementia (NIFD), present significant hurdles due to their vast size and complexity. CompressedMediQ integrates classical high-performance computing (HPC) nodes for advanced MRI pre-processing and Convolutional Neural Network (CNN)-PCA-based feature extraction and reduction, addressing the limited-qubit availability for quantum data encoding in the NISQ (Noisy Intermediate-Scale Quantum) era. This is followed by Quantum Support Vector Machine (QSVM) classification. By utilizing quantum kernel methods, the pipeline optimizes feature mapping and classification, enhancing data separability and outperforming traditional neuroimaging analysis techniques. Experimental results highlight the pipeline's superior accuracy in dementia staging, validating the practical use of quantum machine learning in clinical diagnostics. Despite the limitations of NISQ devices, this proof-of-concept demonstrates the transformative potential of quantum-enhanced learning, paving the way for scalable and precise diagnostic tools in healthcare and signal processing.