ICU Mortality Prediction Using Long Short-Term Memory Networks

Extensive bedside monitoring in Intensive Care Units (ICUs) has resulted in complex temporal data regarding patient physiology, which presents an upscale context for clinical data analysis. In the other hand, identifying the time-series patterns within these data may provide a high aptitude to predict clinical events. Hence, we investigate, during this work, the implementation of an automatic data-driven system, which analyzes large amounts of multivariate temporal data derived from Electronic Health Records (EHRs), and extracts high-level information so as to predict in-hospital mortality and Length of Stay (LOS) early. Practically, we investigate the applicability of LSTM network by reducing the time-frame to 6-hour so as to enhance clinical tasks. The experimental results highlight the efficiency of LSTM model with rigorous multivariate time-series measurements for building real-world prediction engines.

Neuronal Spectral Analysis of EEG and Expert Knowledge Integration for Automatic Classification of Sleep Stages

Being able to analyze and interpret signal coming from electroencephalogram (EEG) recording can be of high interest for many applications including medical diagnosis and Brain-Computer Interfaces. Indeed, human experts are today able to extract from this signal many hints related to physiological as well as cognitive states of the recorded subject and it would be very interesting to perform such task automatically but today no completely automatic system exists. In previous studies, we have compared human expertise and automatic processing tools, including artificial neural networks (ANN), to better understand the competences of each and determine which are the difficult aspects to integrate in a fully automatic system. In this paper, we bring more elements to that study in reporting the main results of a practical experiment which was carried out in an hospital for sleep pathology study. An EEG recording was studied and labeled by a human expert and an ANN. We describe here the characteristics of the experiment, both human and neuronal procedure of analysis, compare their performances and point out the main limitations which arise from this study.