US & MR Image-Fusion Based on Skin Co-Registration

The study and development of innovative solutions for the advanced visualisation, representation and analysis of medical images offer different research directions. Current practice in medical imaging consists in combining real-time US with imaging modalities that allow internal anatomy acquisitions, such as CT, MRI, PET or similar. Application of image-fusion approaches can be found in tracking surgical tools and/or needles, in real-time during interventions. Thus, this work proposes a fusion imaging system for the registration of CT and MRI images with real-time US acquisition leveraging a 3D camera sensor. The main focus of the work is the portability of the system and its applicability to different anatomical districts.

3D Patient-specific Modelling and Characterisation of Muscle-Skeletal Districts

This work addresses the patient-specific characterisation of the morphology and pathologies of muscle-skeletal districts (e.g., wrist, spine) to support diagnostic activities and follow-up exams through the integration of morphological and tissue information. We propose different methods for the integration of morphological information, retrieved from the geometrical analysis of 3D surface models, with tissue information extracted from volume images. For the qualitative and quantitative validation, we will discuss the localisation of bone erosion sites on the wrists to monitor rheumatic diseases and the characterisation of the three functional regions of the spinal vertebrae to study the presence of osteoporotic fractures. The proposed approach supports the quantitative and visual evaluation of possible damages, surgery planning, and early diagnosis or follow-up studies. Finally, our analysis is general enough to be applied to different districts.