Single Image Estimation of Cell Migration Direction by Deep Circular Regression

In this paper we study the problem of estimating the migration direction of cells based on a single image. To the best of our knowledge, there is only one related work that uses a classification CNN for four classes (quadrants). This approach does not allow detailed directional resolution. We solve the single image estimation problem using deep circular regression with special attention to cycle-sensitive methods. On two databases we achieve an average accuracy of $\sim$17 degrees, which is a significant improvement over the previous work.