Achieving Optimal Tissue Repair Through MARL with Reward Shaping and Curriculum Learning

In this paper, we present a multi-agent reinforcement learning (MARL) framework for optimizing tissue repair processes using engineered biological agents. Our approach integrates: (1) stochastic reaction-diffusion systems modeling molecular signaling, (2) neural-like electrochemical communication with Hebbian plasticity, and (3) a biologically informed reward function combining chemical gradient tracking, neural synchronization, and robust penalties. A curriculum learning scheme guides the agent through progressively complex repair scenarios. In silico experiments demonstrate emergent repair strategies, including dynamic secretion control and spatial coordination.

Optimal Path Planning and Cost Minimization for a Drone Delivery System Via Model Predictive Control

In this study, we formulate the drone delivery problem as a control problem and solve it using Model Predictive Control. Two experiments are performed: The first is on a less challenging grid world environment with lower dimensionality, and the second is with a higher dimensionality and added complexity. The MPC method was benchmarked against three popular Multi-Agent Reinforcement Learning (MARL): Independent $Q$-Learning (IQL), Joint Action Learners (JAL), and Value-Decomposition Networks (VDN). It was shown that the MPC method solved the problem quicker and required fewer optimal numbers of drones to achieve a minimized cost and navigate the optimal path.

Predicting Water Quality using Quantum Machine Learning: The Case of the Umgeni Catchment (U20A) Study Region

In this study, we consider a real-world application of QML techniques to study water quality in the U20A region in Durban, South Africa. Specifically, we applied the quantum support vector classifier (QSVC) and quantum neural network (QNN), and we showed that the QSVC is easier to implement and yields a higher accuracy. The QSVC models were applied for three kernels: Linear, polynomial, and radial basis function (RBF), and it was shown that the polynomial and RBF kernels had exactly the same performance. The QNN model was applied using different optimizers, learning rates, noise on the circuit components, and weight initializations were considered, but the QNN persistently ran into the dead neuron problem. Thus, the QNN was compared only by accraucy and loss, and it was shown that with the Adam optimizer, the model has the best performance, however, still less than the QSVC.

Cybercrime Prediction via Geographically Weighted Learning

Inspired by the success of Geographically Weighted Regression and its accounting for spatial variations, we propose GeogGNN -- A graph neural network model that accounts for geographical latitude and longitudinal points. Using a synthetically generated dataset, we apply the algorithm for a 4-class classification problem in cybersecurity with seemingly realistic geographic coordinates centered in the Gulf Cooperation Council region. We demonstrate that it has higher accuracy than standard neural networks and convolutional neural networks that treat the coordinates as features. Encouraged by the speed-up in model accuracy by the GeogGNN model, we provide a general mathematical result that demonstrates that a geometrically weighted neural network will, in principle, always display higher accuracy in the classification of spatially dependent data by making use of spatial continuity and local averaging features.

Predicting Coronary Heart Disease Using a Suite of Machine Learning Models

Coronary Heart Disease affects millions of people worldwide and is a well-studied area of healthcare. There are many viable and accurate methods for the diagnosis and prediction of heart disease, but they have limiting points such as invasiveness, late detection, or cost. Supervised learning via machine learning algorithms presents a low-cost (computationally speaking), non-invasive solution that can be a precursor for early diagnosis. In this study, we applied several well-known methods and benchmarked their performance against each other. It was found that Random Forest with oversampling of the predictor variable produced the highest accuracy of 84%.

Deep Learning Under Siege: Identifying Security Vulnerabilities and Risk Mitigation Strategies

With the rise in the wholesale adoption of Deep Learning (DL) models in nearly all aspects of society, a unique set of challenges is imposed. Primarily centered around the architectures of these models, these risks pose a significant challenge, and addressing these challenges is key to their successful implementation and usage in the future. In this research, we present the security challenges associated with the current DL models deployed into production, as well as anticipate the challenges of future DL technologies based on the advancements in computing, AI, and hardware technologies. In addition, we propose risk mitigation techniques to inhibit these challenges and provide metrical evaluations to measure the effectiveness of these metrics.