Accuracy Improvement of Cell Image Segmentation Using Feedback Former

Semantic segmentation of microscopy cell images by deep learning is a significant technique. We considered that the Transformers, which have recently outperformed CNNs in image recognition, could also be improved and developed for cell image segmentation. Transformers tend to focus more on contextual information than on detailed information. This tendency leads to a lack of detailed information for segmentation. Therefore, to supplement or reinforce the missing detailed information, we hypothesized that feedback processing in the human visual cortex should be effective. Our proposed Feedback Former is a novel architecture for semantic segmentation, in which Transformers is used as an encoder and has a feedback processing mechanism. Feature maps with detailed information are fed back to the lower layers from near the output of the model to compensate for the lack of detailed information which is the weakness of Transformers and improve the segmentation accuracy. By experiments on three cell image datasets, we confirmed that our method surpasses methods without feedback, demonstrating its superior accuracy in cell image segmentation. Our method achieved higher segmentation accuracy while consuming less computational cost than conventional feedback approaches. Moreover, our method offered superior precision without simply increasing the model size of Transformer encoder, demonstrating higher accuracy with lower computational cost.

Generalized SAM: Efficient Fine-Tuning of SAM for Variable Input Image Sizes

There has been a lot of recent research on improving the efficiency of fine-tuning foundation models. In this paper, we propose a novel efficient fine-tuning method that allows the input image size of Segment Anything Model (SAM) to be variable. SAM is a powerful foundational model for image segmentation trained on huge datasets, but it requires fine-tuning to recognize arbitrary classes. The input image size of SAM is fixed at 1024 x 1024, resulting in substantial computational demands during training. Furthermore, the fixed input image size may result in the loss of image information, e.g. due to fixed aspect ratios. To address this problem, we propose Generalized SAM (GSAM). Different from the previous methods, GSAM is the first to apply random cropping during training with SAM, thereby significantly reducing the computational cost of training. Experiments on datasets of various types and various pixel counts have shown that GSAM can train more efficiently than SAM and other fine-tuning methods for SAM, achieving comparable or higher accuracy.