Abstract:Space-Air-Ground Integrated Networks (SAGINs), which incorporate space and aerial networks with terrestrial wireless systems, are vital enablers of the emerging sixth-generation (6G) wireless networks. Besides bringing significant benefits to various applications and services, SAGINs are envisioned to extend high-speed broadband coverage to remote areas, such as small towns or mining sites, or areas where terrestrial infrastructure cannot reach, such as airplanes or maritime use cases. However, due to the limited power and storage resources, as well as other constraints introduced by the design of terrestrial networks, SAGINs must be intelligently configured and controlled to satisfy the envisioned requirements. Meanwhile, Artificial Intelligence (AI) is another critical enabler of 6G. Due to massive amounts of available data, AI has been leveraged to address pressing challenges of current and future wireless networks. By adding AI and facilitating the decision-making and prediction procedures, SAGINs can effectively adapt to their surrounding environment, thus enhancing the performance of various metrics. In this work, we aim to investigate the interplay of AI and SAGINs by providing a holistic overview of state-of-the-art research in AI-enabled SAGINs. Specifically, we present a comprehensive overview of some potential applications of AI in SAGINs. We also cover open issues in employing AI and detail the contributions of SAGINs in the development of AI. Finally, we highlight some limitations of the existing research works and outline potential future research directions.