This study proposes a framework of Uncertainty-based Group Decision Support System (UGDSS). It provides a platform for multiple criteria decision analysis in six aspects including (1) decision environment, (2) decision problem, (3) decision group, (4) decision conflict, (5) decision schemes and (6) group negotiation. Based on multiple artificial intelligent technologies, this framework provides reliable support for the comprehensive manipulation of applications and advanced decision approaches through the design of an integrated multi-agents architecture.