Recently, the leading performance of human pose estimation is dominated by top-down methods. Being a fundamental component in training and inference, data processing has not been systematically considered in pose estimation community, to the best of our knowledge. In this paper, we focus on this problem and find that the devil of top-down pose estimator is in the biased data processing. Specifically, by investigating the standard data processing in state-of-the-art approaches mainly including data transformation and encoding-decoding, we find that the results obtained by common flipping strategy are unaligned with the original ones in inference. Moreover, there is statistical error in standard encoding-decoding during both training and inference. Two problems couple together and significantly degrade the pose estimation performance. Based on quantitative analyses, we then formulate a principled way to tackle this dilemma. Data is processed based on unit length instead of pixel, and an offset-based strategy is adopted to perform encoding-decoding. The Unbiased Data Processing (UDP) for human pose estimation can be achieved by combining the two together. UDP not only boosts the performance of existing methods by a large margin but also plays a important role in result reproducing and future exploration. As a model-agnostic approach, UDP promotes SimpleBaseline-ResNet-50-256x192 by 1.5 AP (70.2 to 71.7) and HRNet-W32-256x192 by 1.7 AP (73.5 to 75.2) on COCO test-dev set. The HRNet-W48-384x288 equipped with UDP achieves 76.5 AP and sets a new state-of-the-art for human pose estimation. The code will be released.