Autonomous checkout systems rely on visual and sensory inputs to carry out fine-grained scene understanding in retail environments. Retail environments present unique challenges compared to typical indoor scenes owing to the vast number of densely packed, unique yet similar objects. The problem becomes even more difficult when only RGB input is available, especially for data-hungry tasks such as instance segmentation. To address the lack of datasets for retail, we present StandardSim, a large-scale photorealistic synthetic dataset featuring annotations for semantic segmentation, instance segmentation, depth estimation, and object detection. Our dataset provides multiple views per scene, enabling multi-view representation learning. Further, we introduce a novel task central to autonomous checkout called change detection, requiring pixel-level classification of takes, puts and shifts in objects over time. We benchmark widely-used models for segmentation and depth estimation on our dataset, show that our test set constitutes a difficult benchmark compared to current smaller-scale datasets and that our training set provides models with crucial information for autonomous checkout tasks.