Generalization remains a major problem in supervised learning of single-channel speech enhancement. In this work, we propose learnable loss mixup (LLM), a simple and effortless training diagram, to improve the generalization of deep learning-based speech enhancement models. Loss mixup, of which learnable loss mixup is a special variant, optimizes a mixture of the loss functions of random sample pairs to train a model on virtual training data constructed from these pairs of samples. In learnable loss mixup, by conditioning on the mixed data, the loss functions are mixed using a non-linear mixing function automatically learned via neural parameterization. Our experimental results on the VCTK benchmark show that learnable loss mixup achieves 3.26 PESQ, outperforming the state-of-the-art.