Science in the Era of ChatGPT, Large Language Models and AI: Challenges for Research Ethics Review and How to Respond

Large language models of artificial intelligence (AI) such as ChatGPT find remarkable but controversial applicability in science and research. This paper reviews epistemological challenges, ethical and integrity risks in science conduct. This is with the aim to lay new timely foundations for a high-quality research ethics review in the era of AI. The role of AI language models as a research instrument and subject is scrutinized along with ethical implications for scientists, participants and reviewers. Ten recommendations shape a response for a more responsible research conduct with AI language models.