We recognize that the skin lesion diagnosis is an essential and challenging sub-task in Image classification, in which the Fisher vector (FV) encoding algorithm and deep convolutional neural network (DCNN) are two of the most successful techniques. Since the joint use of FV and DCNN has demonstrated proven success, the joint techniques could have discriminatory power on skin lesion diagnosis as well. To this hypothesis, we propose the aggregation algorithm for skin lesion diagnosis that utilize the residual network to extract the local features and the Fisher vector method to aggregate the local features to image-level representation. We applied our algorithm on the International Skin Imaging Collaboration 2018 (ISIC2018) challenge and only focus on the third task, i.e., the disease classification.