Privacy-Preserving Dataset Combination

Access to diverse, high-quality datasets is crucial for machine learning model performance, yet data sharing remains limited by privacy concerns and competitive interests, particularly in regulated domains like healthcare. This dynamic especially disadvantages smaller organizations that lack resources to purchase data or negotiate favorable sharing agreements. We present SecureKL, a privacy-preserving framework that enables organizations to identify beneficial data partnerships without exposing sensitive information. Building on recent advances in dataset combination methods, we develop a secure multiparty computation protocol that maintains strong privacy guarantees while achieving >90\% correlation with plaintext evaluations. In experiments with real-world hospital data, SecureKL successfully identifies beneficial data partnerships that improve model performance for intensive care unit mortality prediction while preserving data privacy. Our framework provides a practical solution for organizations seeking to leverage collective data resources while maintaining privacy and competitive advantages. These results demonstrate the potential for privacy-preserving data collaboration to advance machine learning applications in high-stakes domains while promoting more equitable access to data resources.